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Received: 23 Nov , 2013 Accepted: 23 Jan , 2014 Abstract Background & Aims:  Nursing is one of the most stressful jobs in the world. It put a high risk at the mental health of this profession. Considering the importance of physical activity with fitness on mental health, and the crucial role of nursing in the health system, this study was conducted to investigate the relationship between physical activity and general health of nursing personnel in Urmia. Materials & Methods: This descriptive study is a correlation –comparison one which was conducted on 400 nurses who were selected in a multi-stage process. To collect the data, a general health questionnaire, and Beck's physical activity questionnaire were used. To analyze the data, descriptive and inferential statistics (t-test, Pearson correlation coefficient) were used. Result: The results showed that the average physical activity among nurses was lower than the average, and the average mental health of more than half of the subjects were below standard. Also, there is a significant positive relationship between physical activity and general health scores (p

Keywords: Public health, physical activity, nurses

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