Volume 15, Issue 3 (June 2017)                   Nursing and Midwifery Journal 2017, 15(3): 230-243 | Back to browse issues page

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tehranian N, pahlavan F, tork tatari F, asadi E. THE RELATIONSHIP BETWEEN ADIPOKINES AND CYTOKINES WITH POSTPARTUM DEPRESSION: A SYSTEMATIC REVIEW. Nursing and Midwifery Journal 2017; 15 (3) :230-243
URL: http://unmf.umsu.ac.ir/article-1-3176-en.html
THE RELATIONSHIP BETWEEN ADIPOKINES AND CYTOKINES WITH POSTPARTUM DEPRESSION: A SYSTEMATIC REVIEW
Najmeh Tehranian * 1, Fattaneh Pahlavan2 , Fatemeh Tork tatari2 , Elahe Asadi3
1- Assistant Professor, Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tarbiat modares University, Tehran, Iran (Corresponding Author) , tehranian@modares.ac.ir
2- Students of Midwifery, School of Medicine, Tarbiat modares University, Tehran, Iran
3- Graduate student of Public Health, Student Research Committee, School of Health, Isfahan University Medical Sciences, Isfahan
Abstract:   (3722 Views)
Background & Aims: Postpartum depression is a debilitating disorder that occurs in approximately five to ten percent of mothers and half of those will not be detected. Symptoms include persistent crying, anxiety, fatigue, insomnia, discomfort and irritability. The aim of this study was to determine the relationship between postpartum depression with adipokines and cytokines. Materials & Methods: This study is a review with a review of 18 articles derived from 52 articles related to risk factors and the relationship between hormones, adipokines and cytokines with postpartum depression searched the library and reputable online (pubmed, Science Direct, Iran Medex, Pubmed,) the period of 1996-2016was conducted. Result: The evidence indicates an increase in markers of inflammatory and immune system in depressed patients. Adipocytes associated with depression. Ghrelin, leptin and cytokines have been associated with postpartum depression. More studies are needed in relation to adiponectin.Although other adipokines such as orexin, Nesfatin, apelin and hepcidin are associated with depression, but a study in the context of their relationship with postpartum depression are unknown. Conclusion: Given that adipokines and cytokines associated with postpartum depression further attention and research about them as a predictive marker is required.
Keywords: adipokines, cytokines and postpartum depression
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Type of Study: Review article | Subject: روانپزشکی- روان شناسی
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