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Background & Aims: Premenstrual syndrome (PMS) is one of the most common disorders of the luteal phase with a negative effect on fertility and quality of life in women The purpose of this study was to assay the effects of an eight-week training with resistance band and consuming fennel extract on PMS in high school girls. Material & Methods: In this interventional (experimental) research, eighty inactive students suffering from PMS were selected in Shiraz in winter 2020and then randomly categorized to four groups of twenty, including resistance band training, fennel, resistance band training with fennel and control groups after essential descriptions. Resistance band training was performed online three sessions per week (each about 45 minutes) for eight weeks. Fennel was used as oral drops of phenylene 2% daily, 30 drops 2 times a day for two months. Individuals were evaluated with a premenstrual symptom screening tool (PSST) in pre and post-intervention phases. Analysis of variance (ANOVA), analysis of covariance (ANCOVA), dependent t- test, and Tukey's post hoc tests were done for assessing the obtained data (P≤0.05 was assigned as significance level). Results: The results indicated that there were no significant differences between the groups before the intervention but after intervention, there was a significant decrease in the severity of mood-behavioral (7.61±2.31 vs 15.84±3.65) and physical (5.31±1.23 vs 14.72±1.38) symptoms of PMS in experimental groups compared to control (P