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Background & Aims: Due to the lack of direct potential effects and physiological outcomes of each method of weaning from ventilator, none of the weaning methods was recommended on the other. The present study was carried out in order to compare the breathing outcomes of weaning from the ventilator into two methods of ventilation with pressure support and T-piece in patients in the intensive care unit of Urmia Imam Khomeini Educational-Treatment Center in 2017-18. Materials & Methods: This descriptive analytical study After obtaining the Ethics License from the Regional Ethics Committee at the University Research was carried out on 44 patients in the intensive care unit which patients who were eligible to be considered in study, was chosen and were located the number of 22 patients in Group A (weaning by pressure support ventilation) and 22 patients in Group B (weanhng by T-piece method). Data collection were collected using the patients file, the demographic questionnaire and the checklist of the assessment of the respiratory status. Data were analyzed using SPSS software version 20 and descriptive statistics (mean and standard deviation) and analytical tests including parametric tests (T test and ANOVA) and nonparametric (Mann-Whitney, Wilcoxon and Friedman). Results: There was a significant difference between the two weaning groups terms of the two criteria of peak inspiratory pressure and arterial blood oxygen saturation (p0/05). Conclusion: Despite the differences in the peak inspiratory pressure and oxygen saturation of arterial blood between the two groups, there was no significant difference in terms of other weaning outcomes. So doing supplementary studies in this context is recommended.  

Keywords: Intensive care unit, Weaning, Pressure support ventilation, T-piece

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