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Background & Aims: One of the major challenges in methadone maintenance treatment that leads to relapse in patients is lapse. Craving is also the most important factor of lapse and return to drug use after the treatment periods. The aim of this study is to determine the effectiveness of applying continuous care model on lapse and craving of patients that are treated with methadone maintenance therapy in Razi Psychiatric Hospital, Urmia, Iran. Material and Methods: This quasi-experimental study was conducted on 95 patients (N=95) who were selected through the census sampling and randomly assigned to intervention (N=48) and control (N=47) groups. Continuous Care Model which consisted of four stages (orientation, sensitization, control and evaluation) was conducted on intervention group over a period of 3 months. At the end, two groups were compared. Craving questionnaire and lapse-and-absence check list were used to collect the data. The data were analyzed via SPSS.v22 using the dependent and independent t-test and Pearson correlation and Chi-square tests. Results: At the end of third month, the mean of the lapse reached in the experimental group from 2.07±0.89 to 1.57±1.1 and the mean of craving reached from 53.73±13.58 to 50.47±15.1 that showed a significant difference compared to the control group. (P-value

Keywords: Continuous care model, Craving, Relapse, Methadone

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