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 Introduction: AIDS disease has affected 55 million people from whom 19 million have died. Annually, about 6 million have been attacked by AIDS and 2.5 million die. Since there is no vaccine opposite AIDS and there is no certain cure for AIDS, curing prevention and secondary infection is essential.  Purpose: This study was conducted to determine the level of knowledge on AIDS and the way of preventing it among faculty members of Islamic Azad University, Zanjan 2004. Methods & Materials: This descriptive study involves 90 people. Data was collected by a questionnaire in five parts (Demographic questions, factors related to transmission, pathology, complications, and finally prevention of AIDS). Analysing of data was conducted by SPSS software Results: Findings revealed that awareness of faculty members of Islamic Azad University of Zanjan about transmission of disease was 72.2, regarding pathology of disease was 67.7, related to complication of disease was 73.3, and about prevention of disease 74.4.Finally, the knowledge of faculty members of Islamic Azad University of Zanjan was higher than moderate (average %70).  Conclusion: II can be concluded that the rate of awareness is almost satisfactory but it is not enough and it is necessary to perform educational programs

Keywords: AIDS, Prevention, Faculty member, Knowledge

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